alpha Fetoprotein Protein (AA 19-609) (Fc Tag)

N° du produit ABIN7092671

Détail du produit

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Type de proteíne: Recombinant

Attributs du protein: AA 19-609

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette alpha Fetoprotein protéine est marqué à la Fc Tag.

Fonction: Recombinant human AFP protein with C-terminal human Fc tag

Specificité: AFP (Arg19-Val609) hFc (Glu99-Ala330)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Autre désignation: AFP (AFP Produits)

Synonymes: FETA Protein, HPAFP Protein, alpha fetoprotein Protein, alpha-fetoprotein Protein, AFP Protein, Afp Protein

Sujet: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Poids moléculaire: predicted molecular mass of 92.6 kDa after removal of the signal peptide.The apparent molecular mass of AFP-hFc is 100-130 kDa due to glycosylation.

ID gène: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process