IL-21 Protein (AA 30-162) (His tag)

N° du produit ABIN7092721

Détail du produit

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Type de proteíne: Recombinant

Attributs du protein: AA 30-162

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL-21 protéine est marqué à la His tag.

Fonction: Recombinant Human IL21 with C-terminal 6xHis tag

Specificité: IL21 (Gln30-Ser162) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: IL21 (IL21 Produits)

Synonymes: IL-21 Protein, Za11 Protein, interleukin 21 Protein, IL21 Protein, Il21 Protein

Sujet: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Poids moléculaire: predicted molecular mass of 16.3 kDa after removal of the signal peptide.The apparent molecular mass of IL21-His is 15-25 kDa due to glycosylation.

UniProt: Q9HBE4

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response