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CD74 Protein (Fc Tag)

CD74 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7092797
  • Antigène Voir toutes CD74 Protéines
    CD74 (HLA-DR-gamma (CD74))
    Type de proteíne
    Recombinant
    Origine
    • 11
    • 8
    • 3
    Humain
    Source
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD74 protéine est marqué à la Fc Tag.
    Fonction
    Recombinant Human CD74(73-232) Protein with N-terminal human Fc tag
    Specificité
    HFc (Glu99-Ala330) CD74 (Gln73-Met232)
    Attributs du produit
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Pureté
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CD74 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Date de péremption
    12 months
  • Antigène
    CD74 (HLA-DR-gamma (CD74))
    Autre désignation
    CD74 (CD74 Produits)
    Synonymes
    DHLAG Protein, HLADG Protein, II Protein, Ia-GAMMA Protein, CLIP Protein, Ii Protein, INVG34 Protein, Iclp-1 Protein, iclp1 Protein, wu:fb11f09 Protein, wu:fb12a01 Protein, wu:fb13d06 Protein, wu:fk94e07 Protein, Iclp-2 Protein, cd74 Protein, iclp2 Protein, zgc:123161 Protein, CD74 molecule Protein, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Protein, CD74 molecule, major histocompatibility complex, class II invariant chain a Protein, CD74 molecule, major histocompatibility complex, class II invariant chain b Protein, CD74 Protein, Cd74 Protein, cd74a Protein, cd74b Protein
    Sujet
    The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
    Poids moléculaire
    predicted molecular mass of 44.4 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD74(73-232) is 55-70 kDa due to glycosylation.
    UniProt
    P04233
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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