IGFBP7 Protein (AA 30-282) (His tag)

N° du produit ABIN7092833

Détail du produit

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Type de proteíne: Recombinant

Attributs du protein: AA 30-282

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IGFBP7 protéine est marqué à la His tag.

Fonction: Recombinant human IGFBP7 protein with N-terminal 6xHis tag

Specificité: 6xHis tag IGFBP7 (Asp30-Leu282)

Attributs du produit: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Autre désignation: IGFBP7 (IGFBP7 Produits)

Synonymes: zgc:85888 Protein, AGM Protein, FSTL2 Protein, IBP-7 Protein, IGFBP-7 Protein, IGFBP-7v Protein, IGFBPRP1 Protein, MAC25 Protein, PSF Protein, RAMSVPS Protein, TAF Protein, Fstl2 Protein, Mac25 Protein, insulin like growth factor binding protein 7 Protein, insulin-like growth factor binding protein 7 Protein, IGFBP7 Protein, igfbp7 Protein, Igfbp7 Protein

Sujet: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]

Poids moléculaire: predicted molecular mass of 27.0 kDa after removal of the signal peptide. The apparent molecular mass of His-IGFBP7 is 35-40 kDa due to glycosylation.

UniProt: Q16270

Pathways: Growth Factor Binding