Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, His Tag
Séquence
Thr 22 - Gly 614
Attributs du produit
Cynomolgus / Rhesus macaque Cadherin-6, His Tag (CA6-C52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Gly 614 (Accession # G7MUQ7-1). In the region Thr 22 - Gly 614, the AA sequence of Cynomolgus and Rhesus macaque Cadherin-6 are homologus.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.9 kDa. The protein migrates as 80-95 kDa under reducing (R) condition due to glycosylation.
Synonyms: CDH6,CAD6,KCAD,K-cadherin,Cadherin-6, Description: Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.