CLEC5A Protein (His tag)
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- Antigène Voir toutes CLEC5A Protéines
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CLEC5A protéine est marqué à la His tag.
- Fonction
- Human CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified)
- Séquence
- Pro 28 - Lys 188
- Attributs du produit
- Human CLEC5A, His Tag (CLA-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 28 - Lys 188 (Accession # Q9NY25-1).
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Classe de qualité
- MALS verified
- Top Product
- Discover our top product CLEC5A Protéine
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- Indications d'application
- This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 20.3 kDa. The protein migrates as 60-66 kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))
- Autre désignation
- CLEC5A / MDL-1 (CLEC5A Produits)
- Synonymes
- CLECSF5 Protein, MDL-1 Protein, MDL1 Protein, Clecsf5 Protein, Ly100 Protein, Mdl1 Protein, C-type lectin domain containing 5A Protein, C-type lectin domain family 5, member a Protein, CLEC5A Protein, Clec5a Protein
- Sujet
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Synonyms: CLEC5A,CLECSF5,superfamilymember 5,C-type lectin domain family 5, member A,MDL1,MDL-1,DAP12-associating lectin 1,
Description: CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. - Poids moléculaire
- 20.3 kDa
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