NKG2A & CD94 protein (His tag)

N° du produit ABIN7121284

Détail du produit

Antigène: NKG2A & CD94

Type de proteíne: Recombinant

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: His tag

Fonction: Cynomolgus NKG2A&CD94 Protein, His Tag

Séquence: Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94)

Attributs du produit: Cynomolgus NKG2A&CD94, His Tag (NC4-C52H6) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 (NKG2A) & Asp 57 - Ile 179 (CD94) (Accession # Q68VD2-1 (NKG2A) & Q68VD4-1 (CD94).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Indications d'application: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 30.6 kDa. The protein migrates as 35-45 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: NKG2A & CD94

Autre désignation: NKG2A&CD94

Sujet: Synonyms: NKG2A & CD94,
Description: CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

Poids moléculaire: 30.6 kDa