MALS verified
PADI2
Origine: Cynomolgus
Hôte: Cellules d'insectes
Recombinant
>95 % as determined by SDS-PAGE.
Indications d'application
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.4 kDa. The protein migrates as 66-70 kDa under reducing (R) condition .
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4
Stock
-80 °C
Stockage commentaire
-70°C
Antigène
PADI2
(Peptidyl Arginine Deiminase, Type II (PADI2))
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Sujet
Synonyms: PADI2,PAD-H19,KIAA0994,PAD2,PDI2, Description: Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.