HPD Protein (His tag)

N° du produit ABIN7318119

Détail du produit

Antigène: HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HPD protéine est marqué à la His tag.

Fonction: Recombinant Human HPD/4HPPD Protein (His Tag)

Séquence: Met 1-Met393

Attributs du produit: Recombinant Human 4-Hydroxyphenylpyruvate Dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Met393 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 50 mM NaCl, 1 mM DTT, 0.1 mM PMSF, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: HPD (4-Hydroxyphenylpyruvate Dioxygenase (HPD))

Autre désignation: HPD/4HPPD (HPD Produits)

Synonymes: fb58f02 Protein, hpd Protein, wu:fb58f02 Protein, zgc:56326 Protein, zgc:92456 Protein, MGC146689 Protein, BA0240 Protein, PSPTO3553 Protein, DDBDRAFT_0203373 Protein, DDBDRAFT_0231603 Protein, DDBDRAFT_0231604 Protein, DDB_0203373 Protein, DDB_0231603 Protein, DDB_0231604 Protein, hppd Protein, 4-HPPD Protein, 4HPPD Protein, GLOD3 Protein, HPPDASE Protein, PPD Protein, 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE Protein, F12K11.9 Protein, F12K11_9 Protein, HPD Protein, P-HYDROXYPHENYLPYRUVATE DIOXYGENASE Protein, phytoene desaturation 1 Protein, Fla Protein, Flp Protein, Hppd Protein, Laf Protein, 4-hydroxyphenylpyruvate dioxygenase a Protein, 4-hydroxyphenylpyruvate dioxygenase Protein, 4-hydroxyphenylpyruvate dioxygenase b Protein, 4-hydroxyphenylpyruvate dioxygenase L homeolog Protein, 4-hydroxyphenylpyruvic acid dioxygenase Protein, hpda Protein, HPD Protein, hpdb Protein, hpd.L Protein, hpd Protein, BA_0240 Protein, hppD Protein, Hpd Protein, PDS1 Protein

Sujet:

Background: 4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in high levels of tyrosine concentration in the blood, which can cause mild mental retardation at birth, and degradation in vision as a patient grows older.

Synonym: 4-Hydroxyphenylpyruvate Dioxygenase, 4-Hydroxyphenylpyruvic Acid Oxidase, 4HPPD, HPD, HPPDase, HPD, PPD

Poids moléculaire: 47.1 kDa

UniProt: P32754