Afamin Protein (AFM) (His tag)

N° du produit ABIN7319846

Détail du produit

Antigène: Afamin (AFM)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Afamin protéine est marqué à la His tag.

Fonction: Recombinant Human Afamin/AFM (C-6His)

Séquence: Leu22-Asn599

Attributs du produit: Recombinant Human Afamin is produced by our Mammalian expression system and the target gene encoding Leu22-Asn599 is expressed with a 6His tag at the C-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Afamin (AFM)

Autre désignation: Afamin/AFM (AFM Produits)

Synonymes: AFM Protein, ALB2 Protein, ALBA Protein, ALF Protein, Alf Protein, alpha-Alb Protein, afamin Protein, AFM Protein, Afm Protein

Sujet:

Background: Afamin also known as Alpha -Albumin is a secreted monomeric glycoprotein of the Alb/Albumin family of molecules. AFM is known to bind and transport vitamin E family molecules, playing an important role for transporting at the blood-brain-barrier. Afamin has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. AFM also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rational for the observation that bone formation often follows bone resorption. The importance of Afamin in transport of molecules has led to a suggested diagnostic role in various diseases, including pre-eclampsia, ovarian cancer, and both gestational and type-2 diabetes.

Synonym: Afamin, AFM, ALB2, ALB2alpha-Alb, ALBA, ALBAalpha-albumin, ALF, Alpha-Alb, Alpha-albumin

Poids moléculaire: 67.6 kDa

UniProt: P43652