ANG Protéine

N° du produit ABIN7318153

Détail du produit

Antigène: ANG (Angiogenin (ANG))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human Angiogenin/ANG Protein

Séquence: Gln25-Pro147

Attributs du produit: Recombinant Human Angiogenin is produced by our E.coli expression system and the target gene encoding Gln25-Pro147 is expressed.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ANG (Angiogenin (ANG))

Autre désignation: Angiogenin/ANG (ANG Produits)

Synonymes: ALS9 Protein, HEL168 Protein, RNASE4 Protein, RNASE5 Protein, ANG Protein, AI385586 Protein, Ang1 Protein, Rnase5 Protein, Rnase5a Protein, ANG1 Protein, angiogenin Protein, angiogenin, ribonuclease, RNase A family, 5 Protein, ribonuclease A family member k6 Protein, ANG Protein, Ang Protein, RNASE6 Protein

Sujet:

Background: Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.

Synonym: Angiogenin, Ribonuclease 5, RNase 5, ANG, RNASE5

Poids moléculaire: 14.3 kDa

UniProt: P03950