Annexin VIII Protein (His tag)

N° du produit ABIN7317192

Détail du produit

Antigène: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Annexin VIII protéine est marqué à la His tag.

Fonction: Recombinant Human Annexin A8/ANXA8 Protein (His Tag)

Séquence: Met 1-Pro327

Attributs du produit: A DNA sequence encoding the human ANXA8 (AAH73755.1) (Met1-Pro327) was expressed with a polyhistidine tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Autre désignation: Annexin A8/ANXA8 (ANXA8 Produits)

Synonymes: ANX8 Protein, ANXA8L1 Protein, ANXA8L2 Protein, AI466995 Protein, Anx8 Protein, anx8 Protein, MGC85309 Protein, ANXA8 Protein, annexin A8 Protein, annexin A8 S homeolog Protein, ANXA8 Protein, Anxa8 Protein, anxa8.S Protein, LOC694628 Protein, LOC100052045 Protein

Sujet:

Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

Synonym: Annexin A8, Annexin VIII, Annexin-8, Vascular Anticoagulant-Beta, VAC-Beta, ANXA8, ANX8

Poids moléculaire: 39.1 kDa