Biglycan Protein (BGN) (Fc Tag)

N° du produit ABIN7320153

Détail du produit

Antigène: Biglycan (BGN)

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette Biglycan protéine est marqué à la Fc Tag.

Fonction: Recombinant Mouse Biglycan/BGN Protein (Fc Tag)

Séquence: Met1-Lys369

Attributs du produit: A DNA sequence encoding the mouse BGN (Met1-Lys369) was expressed with the Fc region of human IgG1 at the C-terminus.

Pureté: > 85 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Biglycan (BGN)

Autre désignation: Biglycan/BGN (BGN Produits)

Synonymes: DSPG1 Protein, PG-S1 Protein, PGI Protein, SLRR1A Protein, BG Protein, BSPG1 Protein, bgn Protein, zgc:91989 Protein, dspg1 Protein, pg-s1 Protein, slrr1a Protein, xbgn Protein, BGN Protein, zgc:77123 Protein, DKFZp468I2427 Protein, biglycan Protein, biglycan L homeolog Protein, biglycan a Protein, biglycan S homeolog Protein, biglycan b Protein, BGN Protein, Bgn Protein, bgn.L Protein, bgna Protein, bgn.S Protein, bgn Protein, bgnb Protein

Sujet:

Background: Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.

Synonym: BG,DSPG1,PG-S1,PGI,SLRR1A

Poids moléculaire: 66.5 kDa

NCBI Accession: NP_031568

Pathways: Glycosaminoglycan Metabolic Process