Calmodulin 1 Protein (Calm1)

N° du produit ABIN7318225

Détail du produit

Antigène: Calmodulin 1 (Calm1)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human Calmodulin/CALM1 Protein

Séquence: Met 1-Lys149

Attributs du produit: Recombinant Human Calmodulin is produced by our E.coli expression system and the target gene encoding Met1-Lys149 is expressed.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM NH4HCO3, pH 8.0 .

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Calmodulin 1 (Calm1)

Autre désignation: Calmodulin/CALM1 (Calm1 Produits)

Synonymes: AI256814 Protein, AI327027 Protein, AI461935 Protein, AL024000 Protein, CaM Protein, Calm Protein, CaMI Protein, CALML2 Protein, CAMI Protein, CPVT4 Protein, DD132 Protein, LQT14 Protein, PHKD Protein, caM Protein, calm1 Protein, calm2-a Protein, calm2-b Protein, calm2a Protein, calml2 Protein, cami Protein, dd132 Protein, 3909 Protein, CAM Protein, CG8472 Protein, Cal Protein, Cal49A Protein, CalA Protein, Cam1 Protein, D-CaM Protein, DmCaM Protein, DmCalm Protein, Dmel\CG8472 Protein, anon-EST:Posey59 Protein, cam Protein, dCaM Protein, l(2)03909 Protein, l(2)3909 Protein, lincRNA.S2634 Protein, calmodulin 1 Protein, calmodulin 2 Protein, calmodulin 1 (phosphorylase kinase, delta) L homeolog Protein, Calmodulin Protein, Calm1 Protein, Calm2 Protein, CALM1 Protein, calm1.L Protein, Cam Protein

Sujet:

Background: Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.

Synonym: Calmodulin, CaM, CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII

Poids moléculaire: 16.8 kDa

UniProt: P62158

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling