Cathepsin B Protein (CTSB) (His tag)

N° du produit ABIN7320464

Détail du produit

Antigène: Cathepsin B (CTSB)

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette Cathepsin B protéine est marqué à la His tag.

Fonction: Recombinant Mouse Cathepsin B/CTSB Protein (His Tag)

Séquence: His18-Phe339

Attributs du produit: Recombinant Mouse Cathepsin B is produced by our Mammalian expression system and the target gene encoding His18-Phe339 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Cathepsin B (CTSB)

Autre désignation: Cathepsin B/CTSB (CTSB Produits)

Synonymes: APPS Protein, CPSB Protein, CB Protein, apps Protein, cpsb Protein, LOC692390 Protein, CTSB Protein, cathepsin B Protein, cathepsin B S homeolog Protein, CTSB Protein, Ctsb Protein, ctsb.S Protein, LOC692390 Protein

Sujet:

Background: Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.

Synonym: Cathepsin B,Ctsb,Cathepsin B1

Poids moléculaire: 36.4 kDa

UniProt: P10605

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades