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Cathepsin D Protein (CTSD) (His tag)

CTSD Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318253
  • Antigène Voir toutes Cathepsin D (CTSD) Protéines
    Cathepsin D (CTSD)
    Type de proteíne
    Recombinant
    Origine
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Cathepsin D protéine est marqué à la His tag.
    Fonction
    Recombinant Human Cathepsin D/CTSD Protein (His Tag)
    Séquence
    Leu21-Leu412
    Attributs du produit
    Recombinant Human Cathepsin D is produced by our Mammalian expression system and the target gene encoding Leu21-Leu412 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSD Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    Cathepsin D (CTSD)
    Autre désignation
    Cathepsin D/CTSD (CTSD Produits)
    Synonymes
    catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein
    Sujet

    Background: The protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to, but narrower than, that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8 % ) compared with non-demented controls (4.9 %). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family

    Synonym: Cathepsin D, CTSD,CLN10,CPSD,HEL-S-130P

    Poids moléculaire
    43.8 kDa
    UniProt
    P07339
    Pathways
    Peptide Hormone Metabolism
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