CD3D Protein (His tag)
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- Antigène Voir toutes CD3D Protéines
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
- Type de proteíne
- Recombinant
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Origine
- Cynomolgus
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Source
- Human Cells
- Purification/Conjugué
- Cette CD3D protéine est marqué à la His tag.
- Fonction
- Recombinant Cynomolgus CD3d/CD3 delta Protein (His Tag)
- Séquence
- Phe22-Ala105
- Attributs du produit
- Recombinant Cynomolgus CD3d is produced by our Mammalian expression system and the target gene encoding Phe22-Ala105 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 85 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD3D Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
- Autre désignation
- CD3d/CD3 delta (CD3D Produits)
- Synonymes
- CD3-DELTA Protein, T3D Protein, CD3 Protein, T3d Protein, CD3d molecule Protein, CD3 antigen, delta polypeptide Protein, CD3D Protein, Cd3d Protein
- Sujet
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Background: T-cell surface glycoprotein CD3 delta chain (CD3D) is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. CD3 chains are present as CD3gammaepsilon, deltaepsilon, and zetazeta dimers in the receptor complex and play critical roles in the antigen receptor assembly, transport to the cell surface, and the receptor-mediated signal transduction. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs(ITAMs). CD3D contains 1 ITAM domain and has been shown to interact with CD8A.
Synonym: T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain, CD3d, CD3D
- Poids moléculaire
- 10.4 kDa
- UniProt
- Q95LI8
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events
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