CD82 Protein (CD82) (Fc Tag)

N° du produit ABIN7319825

Détail du produit

Antigène: CD82

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CD82 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human CD82 (N-Fc)

Séquence: Gly103-Gln225

Attributs du produit: Recombinant Human CD82 Antigen is produced by our Mammalian expression system and the target gene encoding Gly103-Gln225 is expressed with a Fc tag at the N-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CD82

Autre désignation: CD82 (CD82 Produits)

Synonymes: AA682076 Protein, AL023070 Protein, C33 Protein, IA4 Protein, Kai1 Protein, Tspan27 Protein, 4F9 Protein, GR15 Protein, KAI1 Protein, R2 Protein, SAR2 Protein, ST6 Protein, TSPAN27 Protein, CD82 antigen Protein, CD82 molecule Protein, Cd82 molecule Protein, Cd82 Protein, CD82 Protein

Sujet:

Background: CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

Synonym: CD82 antigenC33, CD82 Molecule, CD82, IA4, IA4C33 antigen, Inducible membrane protein R2, KAI1, KAI1GR15, ST6, ST6tspan-27, Suppressor of tumorigenicity 6 protein, Tetraspanin-27, TSPAN27, Tspan-27, TSPAN274F9

Poids moléculaire: 40.3 kDa

UniProt: P27701

Pathways: Signalisation p53