CCL11 Protéine

N° du produit ABIN7318257

Détail du produit

Antigène: CCL11 (Chemokine (C-C Motif) Ligand 11 (CCL11))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human CCL11/Eotaxin Protein

Séquence: Gly24-Pro97

Attributs du produit: Recombinant Human C-C Motif Chemokine 11 is produced by our E.coli expression system and the target gene encoding Gly24-Pro97 is expressed.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CCL11 (Chemokine (C-C Motif) Ligand 11 (CCL11))

Autre désignation: CCL11/Eotaxin (CCL11 Produits)

Synonymes: SCYA11 Protein, Scya11 Protein, eotaxin Protein, Eotaxin Protein, C-C motif chemokine ligand 11 Protein, chemokine (C-C motif) ligand 11 Protein, CCL11 Protein, Ccl11 Protein

Sujet:

Background: C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.

Synonym: Eotaxin, C-C Motif Chemokine 11, Eosinophil Chemotactic Protein, Small-Inducible Cytokine A11, CCL11, SCYA11

Poids moléculaire: 8.6 kDa

UniProt: P51671

Pathways: Regulation of Actin Filament Polymerization, Phosphorylation & l'infection par le SRAS-CoV-2