CXCL1 Protein (His tag)

N° du produit ABIN7320497

Détail du produit

Antigène: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette CXCL1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse CXCL1 Protein (His Tag)

Séquence: Arg20-Lys96

Attributs du produit: Recombinant Mouse C-X-C motif chemokine 1 is produced by our Mammalian expression system and the target gene encoding Arg20-Lys96 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))

Autre désignation: CXCL1 (CXCL1 Produits)

Synonymes: FSP Protein, GRO1 Protein, GROa Protein, MGSA Protein, MGSA-a Protein, NAP-3 Protein, SCYB1 Protein, CINC-1 Protein, Gro1 Protein, CXCL1 Protein, Sdf1 Protein, Fsp Protein, KC Protein, Mgsa Protein, N51 Protein, Scyb1 Protein, gro Protein, GRO Protein, Gro Protein, C-X-C motif chemokine ligand 1 Protein, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) Protein, C-X-C motif chemokine ligand 12 Protein, chemokine (C-X-C motif) ligand 1 Protein, CXCL1 Protein, Cxcl1 Protein, Cxcl12 Protein, GRO1 Protein

Sujet:

Background: Growth-regulated alpha protein (CXCL1,KC), is a member of the alpha chemokine subfamily, was initially identified as an immediate early gene induced in mouse fibroblasts by platelet-derived growth factor. The N-terminal processed form KC(5-72) of the protein is produced by proteolytic cleavage after secretion from bone marrow stromal cells, and shows a highly enhanced hematopoietic activity. Mouse KC shows approximately 63 % identity to that of mouse MIP-2. KC is also approximately 60 % identical to the human GROs. It has been suggested that mouse KC and MIP-2 are the orthologs of the human GROs and rat CINCs. Cxcl1 has chemotactic activity for neutrophils, and contributes to neutrophil activation during inflammation. Hematoregulatory chemokine, in vitro, suppresses hematopoietic progenitor cell proliferation.

Synonym: Growth-regulated alpha protein,C-X-C motif chemokine 1,Platelet-derived growth factor-inducible protein KC,Secretory protein N51,Cxcl1,Gro, Gro1, Mgsa, Scyb1

Poids moléculaire: 9.4 kDa

UniProt: P12850

Pathways: Autophagy