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Elastase 4 Protein (His tag)

CTRC Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319317
  • Antigène Tous les produits Elastase 4 (CTRC)
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    Type de proteíne
    Recombinant
    Origine
    • 7
    • 3
    • 3
    • 1
    Humain
    Source
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification/Conjugué
    Cette Elastase 4 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Chymotrypsin C Protein (His Tag)
    Séquence
    Cys17-Leu268
    Attributs du produit
    Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    Autre désignation
    Chymotrypsin C (CTRC Produits)
    Synonymes
    CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein
    Sujet

    Background: Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.

    Synonym: Chymotrypsin-C, Caldecrin, CTRC, CLCR

    Poids moléculaire
    29.0 kDa
    UniProt
    Q99895
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