Claudin 11 Protein (CLDN11) (Fc Tag)

N° du produit ABIN7317330

Détail du produit

Antigène: Claudin 11 (CLDN11)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Claudin 11 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human CLDN11/Claudin-11 Protein (Fc Tag)

Séquence: Val23-Arg82

Attributs du produit: A DNA sequence encoding the human CLDN11 (O75508) (Val23-Arg82) was expressed with the Fc region of mouse IgG1 at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Claudin 11 (CLDN11)

Autre désignation: CLDN11/Claudin-11 (CLDN11 Produits)

Synonymes: cldn11 Protein, fb97c11 Protein, wu:fb97c11 Protein, claudin-11 Protein, CLDN11 Protein, Claudin-11 Protein, DKFZp459H2322 Protein, OSP Protein, OTM Protein, Claudin11 Protein, Osp Protein, Otm Protein, claudin 11b Protein, claudin 11 Protein, cldn11b Protein, CLDN11 Protein, Cldn11 Protein

Sujet:

Background: Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central nervous system (CNS) myelin that is necessary for normal CNS function. Human blood-testis barrier disruption is related to a dysfunction of CLDN11 gene. It plays an important role in regulating proliferation and migration of oligodendrocytes.

Synonym: OSP,OTM

Poids moléculaire: 33.2 kDa

UniProt: O75508

Pathways: Hepatitis C