COL4a3 Protein (Fc Tag)
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- Antigène Voir toutes COL4a3 (COL4A3) Protéines
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- Type de proteíne
- Recombinant
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Origine
- Rat
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette COL4a3 protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Rat COL4A3 Protein (Fc Tag)
- Séquence
- Gly1426-His1670
- Attributs du produit
- A DNA sequence encoding the rat COL4A3 (NP_001129231) (Gly1426-His1670) was expressed with Fc region of human IgG1 at the N-terminus.
- Pureté
- > 85 % as determined by SDS-PAGE
- niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- Autre désignation
- COL4A3 (COL4A3 Produits)
- Synonymes
- zTumstatin Protein, [a]3(IV) Protein, alpha3(IV) Protein, collagen type IV alpha 3 chain Protein, collagen, type IV, alpha 3 Protein, COL4A3 Protein, col4a3 Protein, Col4a3 Protein
- Sujet
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Background: COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a head-to-head conformation and each gene pair shares a common promoter.
Synonym: COL4A3
- Poids moléculaire
- 55.2 kDa
- NCBI Accession
- NP_001129231
- Pathways
- Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity
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