CSF3R Protein (Fc Tag)
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- Antigène Voir toutes CSF3R Protéines
- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette CSF3R protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Human G-CSFR/CD114/CSF3R (C-Fc)
- Séquence
- Glu25-His627
- Attributs du produit
- Recombinant Human Granulocyte Colony-stimulating Factor Receptor is produced by our Mammalian expression system and the target gene encoding Glu25-His627 is expressed with a Fc tag at the C-terminus.
- Pureté
- >95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CSF3R Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
- Autre désignation
- G-CSFR/CD114/CSF3R (CSF3R Produits)
- Synonymes
- CD114 Protein, GCSFR Protein, Cd114 Protein, Csfgr Protein, G-CSF-R Protein, G-CSFR Protein, CSF3R Protein, gcsfr Protein, cd114 Protein, colony stimulating factor 3 receptor Protein, colony stimulating factor 3 receptor (granulocyte) Protein, colony stimulating factor 3 receptor L homeolog Protein, granulocyte colony-stimulating factor receptor Protein, CSF3R Protein, Csf3r Protein, csf3r Protein, csf3r.L Protein, LOC100433338 Protein
- Sujet
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Background: Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, the protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis.
Synonym: CD114 antigen, CD114, colony stimulating factor 3 receptor (granulocyte), CSF3R, Csfgr, G-CSF R, G-CSF receptor, GCSFR, G-CSFR, GCSFRG-CSF-R
- Poids moléculaire
- 93.7 kDa
- UniProt
- Q99062
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