DPEP1 Protein (His tag)
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- Antigène Voir toutes DPEP1 Protéines
- DPEP1 (Dipeptidase 1 (Renal) (DPEP1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette DPEP1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human Dipeptidase 1/DPEP1 Protein (His Tag)
- Séquence
- Asp17-Ser385
- Attributs du produit
- Recombinant Human Dipeptidase 1 is produced by our Mammalian expression system and the target gene encoding Asp17-Ser385 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product DPEP1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- DPEP1 (Dipeptidase 1 (Renal) (DPEP1))
- Autre désignation
- Dipeptidase 1/DPEP1 (DPEP1 Produits)
- Synonymes
- AI327012 Protein, MBD Protein, MBD1 Protein, MDP Protein, RDP Protein, dipeptidase 1 (renal) Protein, dipeptidase 1 Protein, DPEP1 Protein, Dpep1 Protein
- Sujet
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Background: Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However, DPEP1 expression decreased with pathological differentiation, lymph-node and distant metastasis.
Synonym: Dipeptidase 1, Dehydropeptidase-I, Microsomal Dipeptidase, Renal Dipeptidase, hRDP, DPEP1, MDP, RDP, MBD1
- Poids moléculaire
- 42.1 kDa
- UniProt
- P16444
- Pathways
- Inositol Metabolic Process
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