EPH Receptor A3 Protein (EPHA3) (His tag)
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- EPH Receptor A3 (EPHA3)
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Rat
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette EPH Receptor A3 protéine est marqué à la His tag.
- Fonction
- Recombinant Rat EphA3 Protein (His Tag)(Active)
- Séquence
- Met1-His541
- Attributs du produit
- A DNA sequence encoding the rat EPHA3 (EDL75897.1) (Met1-His541) was expressed with a polyhistidine tag at the C-terminus.
- Pureté
- > 90 % as determined by SDS-PAGE
- niveau d'endotoxine
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized rat EPHA3-His at 10 μg/ml (100 μl /well) can bind rat EFNA5-Fc, The EC50 of ratEFNA5-Fc is 9-20ng/ml.
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- Discover our top product EPHA3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- EPH Receptor A3 (EPHA3)
- Autre désignation
- EphA3 (EPHA3 Produits)
- Synonymes
- EK4 Protein, ETK Protein, ETK1 Protein, HEK Protein, HEK4 Protein, TYRO4 Protein, EPHA3 Protein, AW492086 Protein, Cek4 Protein, End3 Protein, Hek Protein, Hek4 Protein, Mek4 Protein, Tyro4 Protein, CEK4 Protein, EPH receptor A3 Protein, ephrin type-A receptor 3 Protein, Eph receptor A3 Protein, EPHA3 Protein, LOC100439679 Protein, Epha3 Protein
- Sujet
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Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: EPHA3
- Poids moléculaire
- 61.2 kDa
- Pathways
- Signalisation RTK, Regulation of Cell Size
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