Estrogen Receptor alpha Protein (His tag)
-
- Antigène Voir toutes Estrogen Receptor alpha (ESR1) Protéines
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Estrogen Receptor alpha protéine est marqué à la His tag.
- Fonction
- Recombinant Human Estrogen Receptor α/ER alpha Protein (His Tag)
- Séquence
- Met 1-Gln116
- Attributs du produit
- Recombinant Human Estrogen receptor alpha is produced by our E.coli expression system and the target gene encoding Met1-Gln116 is expressed with a 6His tag at the N-terminus.
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ESR1 Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Antigène
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Autre désignation
- Estrogen Receptor alpha/ER alpha (ESR1 Produits)
- Synonymes
- LOC398734 Protein, AA420328 Protein, AU041214 Protein, ER-alpha Protein, ER[a] Protein, ERa Protein, ERalpha Protein, ESR Protein, Estr Protein, Estra Protein, Nr3a1 Protein, NR3A1 Protein, eralpha Protein, zfER[a] Protein, ER Protein, ESRA Protein, ESTRR Protein, Era Protein, akap12 Protein, cb27 Protein, esr1 Protein, fb72g12 Protein, id:ibd1202 Protein, sb:cb27 Protein, si:ch73-192g21.1 Protein, wu:fb72g12 Protein, wu:fc21c03 Protein, Esr Protein, RNESTROR Protein, ERALPHA Protein, er Protein, esr Protein, nr3a1 Protein, XER Protein, era Protein, esra Protein, ERbeta Protein, xesr-1 Protein, xlERalpha1 Protein, xlERalpha2 Protein, ESR1 Protein, estrogen receptor 1 L homeolog Protein, estrogen receptor 1 (alpha) Protein, estrogen receptor 1 Protein, A kinase (PRKA) anchor protein 12b Protein, esr1.L Protein, Esr1 Protein, ESR1 Protein, esr1 Protein, akap12b Protein
- Sujet
-
Background: Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Synonym: Estrogen Receptor, ER, ER-Alpha, Estradiol Receptor, Nuclear Receptor Subfamily 3 Group A Member 1, ESR1, ESR, NR3A1
- Poids moléculaire
- 14.4 kDa
- UniProt
- P03372
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
-