Fibrillin 1 Protein (FBN1) (His tag)

N° du produit ABIN7319692

Détail du produit

Antigène: Fibrillin 1 (FBN1)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Fibrillin 1 protéine est marqué à la His tag.

Fonction: Recombinant Human Fibrillin-1/FBN1 Protein (His Tag)

Séquence: Ser2732-His287

Attributs du produit: Recombinant Human Fibrillin-1 is produced by our Mammalian expression system and the target gene encoding Ser2732-His2871 is expressed with a 8His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Fibrillin 1 (FBN1)

Autre désignation: Fibrillin-1/FBN1 (FBN1 Produits)

Synonymes: FBN1 Protein, ACMICD Protein, ECTOL1 Protein, FBN Protein, GPHYSD2 Protein, MASS Protein, MFS1 Protein, OCTD Protein, SGS Protein, SSKS Protein, WMS Protein, WMS2 Protein, AI536462 Protein, B430209H23 Protein, Fib-1 Protein, Tsk Protein, fibrillin 1 Protein, FBN1 Protein, Fbn1 Protein

Sujet:

Background: Asprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.

Synonym: Fibrillin-1, FBN1, Asprosin, FBN

Poids moléculaire: 17 kDa

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome