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FRZB Protein (His tag)

FRZB Origine: Humain Hôte: HEK-293 Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
N° du produit ABIN7317893
  • Antigène Voir toutes FRZB Protéines
    FRZB (Frizzled-Related Protein (FRZB))
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 3
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette FRZB protéine est marqué à la His tag.
    Fonction
    Recombinant Human FRZB/sFRP-3 Protein (His Tag)
    Séquence
    Ala32-Asn325
    Attributs du produit
    A DNA sequence encoding the human FRZB (NP_001454.2) (Ala32-Asn325) was expressed with a C-terminal polyhistidine tag.
    Pureté
    > 85 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product FRZB Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    FRZB (Frizzled-Related Protein (FRZB))
    Autre désignation
    FRZB/sFRP-3 (FRZB Produits)
    Synonymes
    Frp Protein, Sfrp3 Protein, frezzled Protein, fritz Protein, frzb-1 Protein, FRE Protein, FRITZ Protein, FRP-3 Protein, FRZB-1 Protein, FRZB-PEN Protein, FRZB1 Protein, FZRB Protein, OS1 Protein, SFRP3 Protein, SRFP3 Protein, hFIZ Protein, Frzb-1 Protein, frizzled-related protein Protein, Frzb Protein, FRZB Protein
    Sujet

    Background: FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis (OA) susceptibility. FRZB may serve an important role in determining hip shape and may modify the relationship between hip shape and OA.

    Synonym: FRE,FRITZ,FRP-3,FRZB-1,FRZB-PEN,FRZB1,FZRB,hFIZ,OS1,SFRP3,SRFP3

    Poids moléculaire
    34.5 kDa
    NCBI Accession
    NP_001454
    Pathways
    Signalisation WNT, Positive Regulation of fat Cell Differentiation
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