Galanin Protein (GAL) (Fc Tag)

N° du produit ABIN7317568

Détail du produit

Antigène: Galanin (GAL)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Galanin protéine est marqué à la Fc Tag.

Fonction: Recombinant Human Galanin/GAL Protein (Fc Tag)

Séquence: Met 1-Ser123

Attributs du produit: A DNA sequence encoding the human GAL (P22466) (Met1-Ser123) was expressed with the Fc region of human IgG1 at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Galanin (GAL)

Autre désignation: Galanin/GAL (GAL Produits)

Synonymes: Galn Protein, galanin and GMAP prepropeptide Protein, galanin Protein, GAL Protein, Gal Protein

Sujet:

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD180, also known as RP105, is a B-cell surface molecule belonging to the family of pathogen receptors, Toll-like receptors (TLR). CD180 has an extracellular leucine-rich repeats and a short cytoplasmic tail. CD180 / RP105 interact with an extracellular molecule named MD1 and then together form the cell surface receptor complex RP105 / MD1 which induces B-cell activation in humans and mice, leading to proliferation and up-regulation of a costimulatory molecule, B7.2 / CD86. CD180 / RP105 also has a role in LPS response because B cells lacking RP105 show hyporesponsiveness to LPS.

Synonym: GAL-GMAP,GALN,GLNN,GMAP

Poids moléculaire: 38.5 kDa

UniProt: P22466

Pathways: Regulation of Hormone Metabolic Process, Feeding Behaviour