Glutathione Synthetase Protein (GSS) (His tag)

N° du produit ABIN7318542

Détail du produit

Antigène: Glutathione Synthetase (GSS)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Glutathione Synthetase protéine est marqué à la His tag.

Fonction: Recombinant Human GSS Protein (His Tag)

Séquence: Ala2-Val474

Attributs du produit: Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: Glutathione Synthetase (GSS)

Autre désignation: GSS (GSS Produits)

Synonymes: PRNP Protein, 6835 Protein, CG32497 Protein, CG33065 Protein, CG6835 Protein, Dmel\\CG6835 Protein, F21A20.90 Protein, F21A20_90 Protein, GLUTATHIONE SYNTHETASE Protein, GSHB Protein, glutathione synthetase 2 Protein, GSHS Protein, AI314904 Protein, GS-A/GS-B Protein, gssls-a Protein, glutathione synthetase Protein, Glutathione Synthetase Protein, glutathione synthetase 2 Protein, glutathione synthetase L homeolog Protein, GSS Protein, GSH2 Protein, Tola_1250 Protein, PC1_3711 Protein, Dd586_3633 Protein, Kvar_0701 Protein, Alvin_0197 Protein, Nhal_0215 Protein, BC1002_0254 Protein, Cseg_4017 Protein, Snov_3844 Protein, Aazo_1904 Protein, M301_2613 Protein, Bresu_0515 Protein, Isop_1460 Protein, Marme_4020 Protein, Thicy_0325 Protein, Sinme_3668 Protein, Mesop_0757 Protein, Gss Protein, gss.L Protein

Sujet:

Background: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

Synonym: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS

Poids moléculaire: 53.5 kDa

UniProt: P48637

Pathways: L'effet Warburg