GAMT Protein (His tag)
-
- Antigène Voir toutes GAMT Protéines
- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette GAMT protéine est marqué à la His tag.
- Fonction
- Recombinant Human GAMT Protein (His Tag)
- Séquence
- Met 1-Gly236
- Attributs du produit
- Recombinant Human Guanidinoacetate N-methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Gly236 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GAMT Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mMDTT, pH 8.0 .
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Antigène
- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
- Autre désignation
- GAMT (GAMT Produits)
- Sujet
-
Background: GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid in brain and body fluids.
Synonym: Guanidinoacetate N-methyltransferase, GAMT, PIG2,TP53I2
- Poids moléculaire
- 29.5 kDa
- UniProt
- Q14353
-