HMBS Protein (His tag)
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- Antigène Voir toutes HMBS Protéines
- HMBS (Hydroxymethylbilane Synthase (HMBS))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette HMBS protéine est marqué à la His tag.
- Fonction
- Recombinant Human HMBS Protein (His Tag)
- Séquence
- Ser2-His361
- Attributs du produit
- Recombinant Human Porphobilinogen Deaminase is produced by our Mammalian expression system and the target gene encoding Ser2-His361 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HMBS Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- HMBS (Hydroxymethylbilane Synthase (HMBS))
- Autre désignation
- HMBS (HMBS Produits)
- Sujet
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Background: Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.
Synonym: Porphobilinogen Deaminase, PBG-D, Hydroxymethylbilane Synthase, HMBS, Pre-Uroporphyrinogen Synthase, HMBS, PBGD, UPS
- Poids moléculaire
- 40.5 kDa
- UniProt
- P08397
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