IL-11 Protein (Fc Tag)
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- Antigène Voir toutes IL-11 (IL11) Protéines
- IL-11 (IL11) (Interleukin 11 (IL11))
- Type de proteíne
- Recombinant
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Origine
- Souris
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Source
- Human Cells
- Purification/Conjugué
- Cette IL-11 protéine est marqué à la Fc Tag.
- Fonction
- Recombinant Mouse Interleukin-11/IL-11 Protein (Fc Tag)
- Séquence
- Pro22-Leu199
- Attributs du produit
- Recombinant Mouse Interleukin-11 is produced by our Mammalian expression system and the target gene encoding Pro22-Leu199 is expressed with a Fc tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IL11 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- IL-11 (IL11) (Interleukin 11 (IL11))
- Autre désignation
- Interleukin-11/IL-11 (IL11 Produits)
- Sujet
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Background: Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.
Synonym: Interleukin-11,Il11,IL-11
- Poids moléculaire
- 46.3 kDa
- UniProt
- P47873
- Pathways
- Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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