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IL-11 Protéine

IL11 Origine: Humain Hôte: Yeast (Pichia pastoris) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319568
  • Antigène Voir toutes IL-11 (IL11) Protéines
    IL-11 (IL11) (Interleukin 11 (IL11))
    Type de proteíne
    Recombinant
    Origine
    • 15
    • 11
    • 2
    • 2
    Humain
    Source
    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Yeast (Pichia pastoris)
    Fonction
    Recombinant Human Interleukin-11/IL-11 Protein
    Séquence
    Gly23-Leu199
    Attributs du produit
    Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL11 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    IL-11 (IL11) (Interleukin 11 (IL11))
    Autre désignation
    Interleukin-11/IL-11 (IL11 Produits)
    Sujet

    Background: Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Synonym: Interleukin-11, IL-11, Adipogenesis Inhibitory Factor, AGIF, Oprelvekin, IL11

    Poids moléculaire
    19 kDa
    UniProt
    P20809
    Pathways
    Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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