Kallikrein 1 Protein (KLK1) (His tag)

N° du produit ABIN7320811

Détail du produit

Antigène: Kallikrein 1 (KLK1)

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette Kallikrein 1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)

Séquence: Pro19-Asp261

Attributs du produit: Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Kallikrein 1 (KLK1)

Autre désignation: Kallikrein 1/KLK1 (KLK1 Produits)

Synonymes: KLKR Protein, Klk6 Protein, hK1 Protein, klkr Protein, kallikrein Protein, 0610007D04Rik Protein, Kal Protein, Klk1b6 Protein, mGk-6 Protein, kallikrein 1 Protein, kallikrein 1 L homeolog Protein, KLK1 Protein, klk1.L Protein, LOC100101620 Protein, Klk1 Protein

Sujet:

Background: Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.

Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6

Poids moléculaire: 27.9 kDa

UniProt: P15947

Pathways: Système du Complément