Kallikrein 11 Protein (KLK11) (His tag)

N° du produit ABIN7319354

Détail du produit

Antigène: Kallikrein 11 (KLK11)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Kallikrein 11 protéine est marqué à la His tag.

Fonction: Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)

Séquence: Glu19-Asn250

Attributs du produit: Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: Kallikrein 11 (KLK11)

Autre désignation: Kallikrein 11/KLK11 (KLK11 Produits)

Synonymes: KLK11 Protein, 2310015I08Rik Protein, Prss20 Protein, TLSP Protein, PRSS20 Protein, kallikrein related peptidase 11 Protein, kallikrein related-peptidase 11 Protein, kallikrein-related peptidase 11 Protein, KLK11 Protein, Klk11 Protein

Sujet:

Background: Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

Synonym: Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP

Poids moléculaire: 26.3 kDa

NCBI Accession: NP_006844

Pathways: Système du Complément