Kallikrein 2 Protein (KLK2) (His tag)
-
- Antigène Voir toutes Kallikrein 2 (KLK2) Protéines
- Kallikrein 2 (KLK2)
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Human Cells
- Purification/Conjugué
- Cette Kallikrein 2 protéine est marqué à la His tag.
- Fonction
- Recombinant Human Kallikrein 2/KLK2 Protein (His Tag)
- Séquence
- Pro19-Pro261
- Attributs du produit
- Recombinant Human Kallikrein 2 is produced by our Mammalian expression system and the target gene encoding Pro19-Pro261 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product KLK2 Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Citrate, 150 mM NaCl, pH 3.5.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Antigène
- Kallikrein 2 (KLK2)
- Autre désignation
- Kallikrein 2/KLK2 (KLK2 Produits)
- Synonymes
- KLK2A2 Protein, hGK-1 Protein, hK2 Protein, KLK2 Protein, Ton Protein, rGK-2 Protein, Klk2 Protein, kallikrein related peptidase 2 Protein, kallikrein-related peptidase 2 Protein, kallikrein-2 Protein, kallikrein 1-related peptidase C2 Protein, KLK2 Protein, LOC748637 Protein, Klk1c2 Protein, LOC100716976 Protein
- Sujet
-
Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.
Synonym: Kallikrein-2, Glandular Kallikrein-1, hGK-1, Tissue Kallikrein-2, KLK2
- Poids moléculaire
- 27.9 kDa
- UniProt
- P20151
- Pathways
- Système du Complément
-