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Kallikrein 2 Protein (KLK2) (His tag)

KLK2 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318697
  • Antigène Voir toutes Kallikrein 2 (KLK2) Protéines
    Kallikrein 2 (KLK2)
    Type de proteíne
    Recombinant
    Origine
    • 7
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Kallikrein 2 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Kallikrein 2/KLK2 Protein (His Tag)
    Séquence
    Pro19-Pro261
    Attributs du produit
    Recombinant Human Kallikrein 2 is produced by our Mammalian expression system and the target gene encoding Pro19-Pro261 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Citrate, 150 mM NaCl, pH 3.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    Kallikrein 2 (KLK2)
    Autre désignation
    Kallikrein 2/KLK2 (KLK2 Produits)
    Synonymes
    KLK2A2 Protein, hGK-1 Protein, hK2 Protein, KLK2 Protein, Ton Protein, rGK-2 Protein, Klk2 Protein, kallikrein related peptidase 2 Protein, kallikrein-related peptidase 2 Protein, kallikrein-2 Protein, kallikrein 1-related peptidase C2 Protein, KLK2 Protein, LOC748637 Protein, Klk1c2 Protein, LOC100716976 Protein
    Sujet

    Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

    Synonym: Kallikrein-2, Glandular Kallikrein-1, hGK-1, Tissue Kallikrein-2, KLK2

    Poids moléculaire
    27.9 kDa
    UniProt
    P20151
    Pathways
    Système du Complément
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