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Kallikrein 7 Protein (KLK7) (His tag)

KLK7 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319371
  • Antigène Voir toutes Kallikrein 7 (KLK7) Protéines
    Kallikrein 7 (KLK7)
    Type de proteíne
    Recombinant
    Origine
    • 12
    • 5
    • 3
    Humain
    Source
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette Kallikrein 7 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Kallikrein 7/KLK7 Protein (His Tag)
    Séquence
    Glu23-His252
    Attributs du produit
    Recombinant Human Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Glu23-His252 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK7 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM HEPES, 150 mM NaCl, pH 7.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    Kallikrein 7 (KLK7)
    Autre désignation
    Kallikrein 7/KLK7 (KLK7 Produits)
    Synonymes
    Prss6 Protein, SCCE Protein, PRSS6 Protein, hK7 Protein, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) Protein, kallikrein-related peptidase 7 Protein, kallikrein related peptidase 7 Protein, Klk7 Protein, KLK7 Protein
    Sujet

    Background: Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.

    Synonym: Kallikrein-7, hK7, Serine Protease 6, Stratum Corneum Chymotryptic Enzyme, hSCCE, KLK7, PRSS6, SCCE

    Poids moléculaire
    26.2 kDa
    UniProt
    P49862
    Pathways
    Système du Complément
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