MESDC2 Protein (His tag)
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- Antigène Voir toutes MESDC2 Protéines
- MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MESDC2 protéine est marqué à la His tag.
- Fonction
- Recombinant Human MESDC2/MESD Protein (His Tag)
- Séquence
- Ala 34-Lys 230
- Attributs du produit
- A DNA sequence encoding the human MESDC2 (NP_055969.1) (Ala 34-Lys 230) was fused with a signal peptide at the N-terminus and a polyhistidine tag at the C-terminus.
- Pureté
- > 97 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MESDC2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
- Autre désignation
- MESDC2/MESD (MESDC2 Produits)
- Synonymes
- MGC115616 Protein, MESDC2 Protein, BOCA Protein, MESD Protein, 2210015O11Rik Protein, AW537813 Protein, mKIAA0081 Protein, mesd Protein, msd Protein, zgc:158636 Protein, mesoderm development LRP chaperone Protein, mesoderm development LRP chaperone L homeolog Protein, mesoderm development candidate 2 Protein, MESD Protein, mesd.L Protein, CpipJ_CPIJ010816 Protein, Tsp_04045 Protein, mesd Protein, Mesd Protein, MESDC2 Protein
- Sujet
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Background: LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.
Synonym: BOCA,MESD
- Poids moléculaire
- 23.6 kDa
- NCBI Accession
- NP_055969
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