MOG Protein (AA 30-149) (His tag)
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- Antigène Voir toutes MOG Protéines
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 30-149
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette MOG protéine est marqué à la His tag.
- Fonction
- Recombinant Human MOG Protein (aa 30-149, His Tag)
- Séquence
- Gly 30-Tyr 149
- Attributs du produit
- A DNA sequence encoding the extracellular domain of human MOG (NP_996532.2) (Gly 30-Tyr 149) was expressed, fused with a polyhistidine tag at the C-terminus and an additional Met at the N-terminus.
- Pureté
- > 97 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MOG Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- MOG (Myelin Oligodendrocyte Glycoprotein (MOG))
- Autre désignation
- MOG (MOG Produits)
- Synonymes
- MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein
- Sujet
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Background: Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to immunoglobulin superfamily, and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1 % total proteins) in oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce a demyelinating multiple sclerosis-like disease in experimental animals.
Synonym: Myelin-Oligodendrocyte Glycoprotein, MOG,BTN6,BTNL11,MOGIG2,NRCLP7
- Poids moléculaire
- 15 kDa
- NCBI Accession
- NP_996532
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