NCALD Protein (His tag)

N° du produit ABIN7318816

Détail du produit

Antigène: NCALD (Neurocalcin delta (NCALD))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NCALD protéine est marqué à la His tag.

Fonction: Recombinant Human Neurocalcin-δ/NCALD Protein (His Tag)

Séquence: Met 1-Phe193

Attributs du produit: Recombinant Human Neurocalcin-delta is produced by our E.coli expression system and the target gene encoding Met1-Phe193 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, 40 % Glycerol, pH 8.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: NCALD (Neurocalcin delta (NCALD))

Autre désignation: Neurocalcin-delta/NCALD (NCALD Produits)

Synonymes: AI848120 Protein, D030020D09Rik Protein, D15Ertd412e Protein, nca Protein, NCALD Protein, zgc:175182 Protein, ncald Protein, zgc:100982 Protein, neurocalcin delta Protein, neurocalcin delta L homeolog Protein, Neurocalcin delta Protein, neurocalcin delta a Protein, neurocalcin delta b Protein, Ncald Protein, NCALD Protein, ncald.L Protein, Bm1_53910 Protein, LOAG_16127 Protein, ncald Protein, ncalda Protein, ncaldb Protein

Sujet:

Background: Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.

Synonym: Neurocalcin-Delta, NCALD

Poids moléculaire: 24.4 kDa

UniProt: P61601