NFASC Protein (His tag)

N° du produit ABIN7317169

Détail du produit

Antigène: NFASC (Neurofascin (NFASC))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NFASC protéine est marqué à la His tag.

Fonction: Recombinant Human NFASC/Neurofascin protein (His Tag)

Séquence: Met 1-Gln939

Attributs du produit: A DNA sequence encoding the human NFASC (O94856-12) (Met1-Gln939) was expressed with a C-terminal polyhistidine tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: NFASC (Neurofascin (NFASC))

Autre désignation: NFASC/Neurofascin (NFASC Produits)

Synonymes: sc:d0205 Protein, NF Protein, NRCAML Protein, AA387016 Protein, D430023G06Rik Protein, mKIAA0756 Protein, neurofascin Protein, neurofascin homolog (chicken) a Protein, NFASC Protein, nfasca Protein, Nfasc Protein

Sujet:

Background: NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.

Synonym: NF,NRCAML

Poids moléculaire: 104.4 kDa

Pathways: Cell-Cell Junction Organization