Neuroligin 3 Protein (NLGN3) (His tag)

N° du produit ABIN7317636

Détail du produit

Antigène: Neuroligin 3 (NLGN3)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Neuroligin 3 protéine est marqué à la His tag.

Fonction: Recombinant Human Neuroligin-3/NLGN3 Protein (His Tag)

Séquence: Met 1-Ser 689

Attributs du produit: A DNA sequence encoding the human NLGN3 isoform 2 (Q9NZ94-2) extracellular domain (Met 1-Ser 689) was expressed, fused with a polyhistidine tag at the C-terminus.

Pureté: > 92 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Neuroligin 3 (NLGN3)

Autre désignation: Neuroligin-3/NLGN3 (NLGN3 Produits)

Synonymes: Nlgn3 Protein, GB18290 Protein, hnl3 Protein, NLGN3 Protein, CCE-L1 Protein, NV16744 Protein, Nv1604741 Protein, HNL3 Protein, A230085M13Rik Protein, NL3 Protein, neuroligin 3 Protein, neuroligin 3 S homeolog Protein, NLG-3 Protein, nlgn3.S Protein, NLGN3 Protein, LOC659852 Protein, LOC100121155 Protein, nlgn3 Protein, Nlgn3 Protein

Sujet:

Background: Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface proteins that interact with neurexins (beta-Nxs), another class of neuronal cell-surface proteins, one of each class functioning together in synapse formation. Neuroligins control the formation and functional balance of excitatory and inhibitory synapses in hippocampal neurons. NLGN1 and NLGN2 isoforms are concentrated at glutamatergic and GABAergic synapses, respectively, but the cellular expression and synaptic localization of the endogenous. NLGN3 was enriched in brain, where NLGN3 protein levels increased during postnatal development, coinciding with the peak of synaptogenesis. The NLGN3 is a synaptic adhesion molecule that is a shared component of glutamatergic and GABAergic synapses. Mutations in NLGN3 gene may be associated with autism and Asperger syndrome.

Synonym: HNL3

Poids moléculaire: 74 kDa

Pathways: Synaptic Membrane