Neuroligin 4 Protein (NLGN4) (His tag)

N° du produit ABIN7318817

Détail du produit

Antigène: Neuroligin 4 (NLGN4)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette Neuroligin 4 protéine est marqué à la His tag.

Fonction: Recombinant Human NLGN4X Protein (His Tag)

Séquence: Gln42-Ser676

Attributs du produit: Recombinant Human Neuroligin 4, X-Linked is produced by our Mammalian expression system and the target gene encoding Gln42-Ser676 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Neuroligin 4 (NLGN4)

Autre désignation: NLGN4X (NLGN4 Produits)

Synonymes: ASPGX2 Protein, AUTSX2 Protein, HLNX Protein, HNL4X Protein, NLGN4 Protein, nlgn4 Protein, NLGN4X Protein, Nlgn4x Protein, neuroligin 4, X-linked Protein, neuroligin-4, X-linked Protein, NLGN4X Protein, nlgn4x Protein, LOC100714631 Protein

Sujet:

Background: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.

Synonym: Neuroligin-4 X-Linked, Neuroligin X, HNLX, NLGN4X, KIAA1260, NLGN4

Poids moléculaire: 72.5 kDa

UniProt: Q8N0W4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane