NPTN Protein (His tag)

N° du produit ABIN7318820

Détail du produit

Antigène: NPTN (Neuroplastin (NPTN))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette NPTN protéine est marqué à la His tag.

Fonction: Recombinant Human Neuroplastin/NPTN Protein (His Tag)

Séquence: Gln29-His220

Attributs du produit: Recombinant Human Neuroplastin is produced by our Mammalian expression system and the target gene encoding Gln29-His220 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: NPTN (Neuroplastin (NPTN))

Autre désignation: Neuroplastin/NPTN (NPTN Produits)

Synonymes: SDFR1 Protein, GP55 Protein, GP65 Protein, SDR1 Protein, np55 Protein, np65 Protein, AW554172 Protein, Sdfr1 Protein, nptn Protein, zgc:77326 Protein, neuroplastin Protein, neuroplastin L homeolog Protein, neuroplastin b Protein, NPTN Protein, Nptn Protein, nptn.L Protein, nptnb Protein

Sujet:

Background: Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.

Synonym: Neuroplastin, Stromal Cell-Derived Receptor 1, SDR-1, NPTN, SDFR1, SDR1

Poids moléculaire: 22.7 kDa

UniProt: Q9Y639

Pathways: Regulation of long-term Neuronal Synaptic Plasticity