Neurotrophin 3 Protein (NTF3)

N° du produit ABIN7318822

Détail du produit

Antigène: Neurotrophin 3 (NTF3)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human Neurotrophin-3/NTF3 Protein (Active)

Séquence: Tyr139-Thr 257

Attributs du produit: Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Human NT-3 at 10ug/ml(100 μl/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml .

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Neurotrophin 3 (NTF3)

Autre désignation: Neurotrophin-3/NTF3 (NTF3 Produits)

Synonymes: HDNF Protein, NGF-2 Protein, NGF2 Protein, NT3 Protein, NT-3 Protein, wu:fl98d04 Protein, hdnf Protein, ngf-2 Protein, ngf2 Protein, nt-3 Protein, nt3 Protein, NTF3 Protein, AI316846 Protein, AI835689 Protein, Nt3 Protein, Ntf-3 Protein, neurotrophin 3 Protein, neurotrophin 3 S homeolog Protein, neurotrophin 3 L homeolog Protein, NTF3 Protein, ntf3 Protein, ntf3.S Protein, Ntf3 Protein, ntf3.L Protein

Sujet:

Background: Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.

Synonym: Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3

Poids moléculaire: 13.6 kDa

UniProt: P20783

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway