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Osteomodulin Protein (OMD) (His tag)

OMD Origine: Souris Hôte: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
N° du produit ABIN7320274
  • Antigène Voir toutes Osteomodulin (OMD) Protéines
    Osteomodulin (OMD)
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 1
    • 1
    Souris
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Osteomodulin protéine est marqué à la His tag.
    Fonction
    Recombinant Mouse Osteomodulin/OMD Protein (His Tag)
    Séquence
    Met 1-Ile 423
    Attributs du produit
    A DNA sequence encoding the mouse OMD (NP_036180.1) (Met 1-Ile 423) precusor was expressed, with a C-terminal polyhistidine tag.
    Pureté
    > 96 % as determined by SDS-PAGE
    niveau d'endotoxine
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product OMD Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    Osteomodulin (OMD)
    Autre désignation
    Osteomodulin/OMD (OMD Produits)
    Synonymes
    si:ch211-103f16.5 Protein, OMD Protein, OSAD Protein, SLRR2C Protein, osteomodulin Protein, omd Protein, OMD Protein, Omd Protein
    Sujet

    Background: Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein which belongs to the small leucine-rich proteoglycan (SLRP) family and Class II subfamily. SLRP family proteins are normally found in extracellular matrices, but Osteomodulin is the only member restricted to mineralized tissues. Osteomodulin is primarily expressed by osteoblasts and might have a role in regulation of mineralization. In bone OSAD has been localized in primary spongiosa within the bovine fetal rib growth plate. Moreover, in situ hybridization has shown expression of OSAD in osteoblasts close to the cartilage and bone border in the growth plate of rat femur. OSAD may play an important role during tooth development and biomineralization of dentin. Osteomodulin is a cell binding keratan sulfate proteoglycan which was recently isolated from mineralized bovine bone and subsequently cloned and sequenced. Osteomodulin may be implicated in biomineralization processes. It has a function in binding of osteoblasts via the alpha (V) beta (3)-integrin. It is likely that Osteomodulin is an osteoblast maturation marker that is induced by osteoclast activity. Osteomodulin is also an early marker for terminally differentiated matrix producing osteoblasts.

    Synonym: OSAD,SLRR2C

    Poids moléculaire
    48.8 kDa
    NCBI Accession
    NP_036180
    Pathways
    Glycosaminoglycan Metabolic Process
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