PSPH Protein (His tag)

N° du produit ABIN7318903

Détail du produit

Antigène: PSPH (Phosphoserine Phosphatase (PSPH))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PSPH protéine est marqué à la His tag.

Fonction: Recombinant Human PSPH Protein (His Tag)

Séquence: Met 1-Glu225

Attributs du produit: Recombinant Human Phosphoserine Phosphatase is produced by our E.coli expression system and the target gene encoding Met1-Glu225 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM Tris, 250 mM NaCl, 50 mM Imidazole, pH 8.5 .

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: PSPH (Phosphoserine Phosphatase (PSPH))

Autre désignation: PSPH (PSPH Produits)

Synonymes: PSP Protein, PSPHD Protein, AI480570 Protein, PSPase Protein, PSPH Protein, psph Protein, MGC78828 Protein, zgc:112414 Protein, DDBDRAFT_0183847 Protein, DDBDRAFT_0230054 Protein, DDB_0183847 Protein, DDB_0230054 Protein, phosphoserine phosphatase Protein, phosphoserine phosphatase L homeolog Protein, PSP; O-phosphoserine phosphohydrolase; PSPase Protein, phosphoserine phosphatase SerB Protein, BPI fold containing family A member 2 Protein, PSPH Protein, Psph Protein, psph.L Protein, psph Protein, serB Protein, serB-1 Protein, LOC5568588 Protein, PSP Protein, Svir_29300 Protein, MMAH_RS03435 Protein, BPIFA2 Protein

Sujet:

Background: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.

Synonym: Phosphoserine Phosphatase, PSP, PSPase, L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSPH

Poids moléculaire: 26.1 kDa

UniProt: P78330

Pathways: L'effet Warburg