PRCP Protein (His tag)

N° du produit ABIN7318751

Détail du produit

Antigène: PRCP (Prolylcarboxypeptidase (PRCP))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette PRCP protéine est marqué à la His tag.

Fonction: Recombinant Human PRCP Protein (His Tag)

Séquence: Leu22-His496

Attributs du produit: Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc,150 mM NaCl,10 % Glycerol, pH 4.5.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: PRCP (Prolylcarboxypeptidase (PRCP))

Autre désignation: PRCP (PRCP Produits)

Synonymes: OI13 Protein, PCOLC Protein, PCP Protein, PCP2 Protein, TLD Protein, humpcp Protein, MGC145178 Protein, 2510048K03Rik Protein, 2610104A14Rik Protein, AI451719 Protein, HUMPCP Protein, zgc:91816 Protein, bone morphogenetic protein 1 Protein, prolylcarboxypeptidase Protein, lysosomal Pro-X carboxypeptidase Protein, prolylcarboxypeptidase (angiotensinase C) Protein, BMP1 Protein, prcp Protein, LOC5579822 Protein, CpipJ_CPIJ006123 Protein, CpipJ_CPIJ006124 Protein, Prcp Protein, PRCP Protein

Sujet:

Background: Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH , but enzymatic activity is retained with some substrates at neutral pH . PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.

Synonym: Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PRCP, PRCP, PCP

Poids moléculaire: 54.5 kDa

UniProt: P42785